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Reflections on Lukács’ realist view of literature from a literary-critical and philosophical perspective Lukács literarycritical literary critical
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Zhang, Hui

Trans/Form/Ação

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2024, Volume 47 Nº 1 elocation e0240004

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen: En la era del cientificismo, no es sorprendente revivir la visión realista de Lukács de la literatura. Aunque algunos estudiosos han criticado su visión holística, a juzgar por la preocupación por la realidad de la vida humana y la crítica de la realidad social, su visión realista de la literatura es exactamente lo que los tiempos necesitan. En el contexto del postmodernismo, cuando se critica su visión universal e ideológica del pueblo, se ignora la utilidad de esta visión universal para lograr los efectos realistas de la crítica literaria basada en la visión universal irracional. Su "realismo" no es lo mismo que la "imitación" del realismo clásico, ni la "reproducción" del realismo crítico. La creación artística, incluida la literatura, no es solo una simple adhesión a la realidad social, sino un reflejo de la realidad social histórica general a través de prototipos. Resumen cientificismo holística necesitan postmodernismo pueblo irracional "realismo imitación "imitación clásico reproducción "reproducción crítico artística prototipos

Abstract: In the age of scientism, it is not a surprise to revisit Lukács’ realist view of literature. Although some scholars have criticized his holism view, his realist view of literature is exactly what the times need, in terms of its concern for the reality of human life and its criticism of social reality. This general view is useful in realizing the realistic effect of literary criticism based on the criticism of an irrational general view. However, people overlook this point when criticizing his general and ideological view. His “realism” is not the same as the “imitation” of classical realism, nor is it the same as the “reproduction” of critical realism. The creation of art, including literature, is not just a simple adherence to social reality, but a reflection of the overall historical social reality through archetypes. Abstract scientism Lukács need However realism “realism imitation “imitation reproduction “reproduction art archetypes

https://doi.org/10.1590/0101-3173.2024.v47.n1.e0240004

Correlation between dysphagia and serum albumin levels and prognosis: a retrospective study
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Zhang, Ping-Ping

; Feng, Hai-Yang

; Lu, De-Zhi

; Li, Ting-Ting

; Zhang, Hui

; Wang, Xiao-Wen

; Liu, Wen-Bo

Nutrición Hospitalaria

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Out 2023, Volume 40 Nº 5 Páginas 1025 - 1032

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Introduction: dysphagia is a common complication of stroke, and serum albumin is widely recognized as a strong prognostic marker of health and/or disease status. However, the correlation between dysphagia and serum albumin levels has not been established. Objectives: to observe the correlation between dysphagia and serum albumin levels and prognosis in patients with stroke. Methods: we performed a retrospective study of patients hospitalized between June 1, 2018, and June 1, 2022. A total of 1,370 patients were enrolled. The patients were divided into two groups: dysphagia and non-dysphagia. Binary logistic regression and multiple linear regression models were used to analyze the correlation between dysphagia, albumin, modified Rankin Scale (mRS), activities of daily living (ADL), and length of hospital stay (LOS). Results: after adjusting for confounding factors, the risk of pneumonia in the dysphagia group was 2.417 times higher than that in the non-dysphagia group (OR = 2.417, 95 % CI: 1.902-3.072, p = 0.000). The risk of mRS ≥ 3 and modified Barthel index (MBI) < 60 in patients with dysphagia was 3.272-fold (OR = 3.272, 95 % CI: 2.508-4.269, p < 0.001) and 1.670-fold (OR = 1.670, 95 % CI: 1.230-2.268, p < 0.001), respectively; and the risk of hypoproteinemia was 2.533 times higher (OR = 2.533, 95 % CI: 1.879-3.414, p = 0.000). Stepwise linear regression showed that dysphagia was significantly correlated with lower albumin levels and higher mRS, lower ADL, and longer LOS in patients with stroke (β = -0.220, β = 0.265, β = -0.210, and β = 0.147, respectively; p < 0.001). Conclusions: dysphagia in patients with stroke is associated with decreased albumin levels and has an impact on its prognosis.

Resumen Introducción: la disfagia es una complicación común del accidente cerebrovascular, y la albúmina sérica es ampliamente reconocida como un fuerte marcador pronóstico del estado de salud y/o enfermedad. Sin embargo, no se ha establecido la correlación entre la disfagia y los niveles de albúmina sérica. Objetivos: observar la correlación entre la disfagia y los niveles de albúmina sérica y el pronóstico en pacientes con accidente cerebrovascular. Métodos: realizamos un estudio retrospectivo de pacientes hospitalizados entre el 1 de junio de 2018 y el 1 de junio de 2022. Se inscribieron un total de 1.370 pacientes, los cuales fueron divididos en dos grupos: con disfagia y sin disfagia. Se utilizaron modelos de regresión logística binaria y de regresión lineal múltiple para analizar la correlación entre la disfagia, la albúmina, la escala de Rankin modificada (ERm), las actividades de la vida diaria (AVD) y el tiempo de estancia hospitalaria (TEH). Resultados: después de ajustar por factores de confusión, el riesgo de neumonía en el grupo de disfagia fue 2,417 veces mayor que en el grupo sin disfagia (OR = 2,417, IC 95 %: 1,902-3,072, p = 0,000). El riesgo de ERm ≥ 3 y el índice de Barthel modificado (MBI) < 60 en pacientes con disfagia se multiplicó por 3,272 veces (OR = 3,272, IC 95 %: 2,508-4,269, p < 0,001) y 1,670 veces (OR = 1,670, IC 95 %: 1,230-2,268, p < 0,001), respectivamente; el riesgo de hipoproteinemia fue 2,533 veces mayor (OR = 2,533, IC 95 %: 1,879-3,414, p = 0,000). La regresión lineal por pasos mostró que la disfagia se correlacionó significativamente con niveles más bajos de albúmina y ERm más altos, AVD más bajos y TEH más prolongados en pacientes con accidente cerebrovascular (β = -0,220, β = 0,265, β = -0,210 y β = 0,147, respectivamente; p < 0,001). Conclusiones: la disfagia en pacientes con accidente cerebrovascular se asocia a una disminución de los niveles de albúmina y repercute en su pronóstico.

https://doi.org/10.20960/nh.04444

CHERRY EXTRACT ON POST-EXERCISE MUSCLE DAMAGE
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Zhang, Hui

; Zhu, Mingjiang

; Li, Yuanjing

; Zhang, Chengyun

; Bie, Yejun

; Liu, Haishan

Revista Brasileira de Medicina do Esporte

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2023, Volume 29 elocation e2022_0406

Resumo: En Es Pt | Texto: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Introduction: Cherry extract has a high amount of anthocyanins and flavonoids containing antioxidant effects. Its high antioxidant characteristics have been shown to reduce markers of delayed muscle soreness (DOMS) and exercise-induced muscle damage (EIMD) to improve recovery after exercise. Objective: Verify the effects of the cherry extract on post-exercise muscle damage. Methods: Google scholar, Medline, and Scopus were systematically searched until February 2022. The Cochrane Collaboration tool was applied to determine the risks of bias. Results: The results showed that cherry extract administration did not have a decreasing impact on creatine kinase levels overall: (WMD = 12.85 IU. L-1, 95% CI: −35.94, 61.64; P = 0.606). Considerable heterogeneity was observed among the articles (Cochran's Q-test = 990.80, P = 0.000, I2 = 96.7 %). However, there is a significant reducing effect on pain sensation by the consumption of cherry extract (WMD = −6.105 mm; 95% CI: −11.193 −1.017; p = 0.019). Conclusion: Cherry extract consumption effectively reduced late-onset muscle pain among participants in the overall and subgroup analysis. Thus, the cherry extract may be a complementary alternative in recovery after exercise. Level of evidence II; Therapeutic studies - Manuscript review.

RESUMEN Introducción: El extracto de cereza tiene una gran cantidad de antocianinas y flavonoides con efectos antioxidantes. Se ha demostrado que sus altas características antioxidantes reducen los marcadores de dolor muscular retardado (DOMS) y el daño muscular inducido por el ejercicio (EIMD) para mejorar la recuperación después del ejercicio. Objetivo: Verificar los efectos del extracto de cereza en el daño muscular posterior al ejercicio. Métodos: Se realizaron búsquedas sistemáticas en Google scholar, Medline y Scopus hasta febrero de 2022. Se aplicó la herramienta de colaboración Cochrane para determinar los riesgos de sesgo. Resultados: Los resultados mostraron que la administración de extracto de cereza no tuvo un impacto decreciente en los niveles de creatina quinasa en general: (WMD = 12,85 UI. L-1, IC del 95%: −35,94, 61,64; P = 0,606). Se observó una considerable heterogeneidad entre los artículos (prueba Q de Cochran = 990,80, P = 0,000, I2 = 96,7 %). Sin embargo, el consumo de extracto de cereza tiene un efecto significativo de reducción del dolor (WMD = −6,105 mm; IC del 95%: −11,193 −1,017; p = 0,019). Conclusión: El consumo de extracto de cereza fue eficaz para reducir el dolor muscular de aparición tardía entre los participantes en el análisis global y de subgrupos. Así, el extracto de cereza puede ser una alternativa complementaria en la recuperación después de los ejercicios. Nivel de evidencia II; Estudios terapéuticos - Revisión de manuscritos.

RESUMO Introdução: O extrato de cereja tem uma alta quantidade de antocianinas e flavonóides contendo efeitos antioxidantes. Suas altas características antioxidantes demonstraram reduzir os marcadores de dor muscular retardada (DOMS) e dano muscular induzido pelo exercício (EIMD) para melhorar a recuperação após o exercício. Objetivo: Verificar os efeitos do extrato de cereja nos danos musculares pós-exercício. Métodos: Google scholar, Medline e Scopus foram sistematicamente pesquisados até fevereiro de 2022. A ferramenta de colaboração da Cochrane foi aplicada para determinar os riscos de viés. Resultados: Os resultados mostraram que a administração do extrato de cereja não teve um impacto decrescente nos níveis de creatina quinase em geral: (WMD = 12,85 IU. L-1, 95% CI: −35,94, 61,64; P = 0,606). Uma heterogeneidade considerável foi observada entre os artigos (teste Q da Cochran = 990,80, P = 0,000, I2 = 96,7 %). Porém, há um efeito redutor significativo na sensação de dor pelo consumo de extrato de cereja (WMD = −6,105 mm; 95% CI: −11,193 −1,017; p = 0,019). Conclusão: O consumo de extrato de cereja foi efetivo na redução de dores musculares de início tardio entre os participantes, na análise geral e nos subgrupos. Assim, o extrato de cereja pode ser uma alternativa complementar na recuperação após os exercícios. Nível de evidência II; Estudos terapêuticos - Revisão de manuscritos.

https://doi.org/10.1590/1517-8692202329012022_0406

Comparison of the different monosodium urate crystals in the preparation process and pro-inflammation
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Yan, Fei

; Zhang, Hui

; Yuan, Xuan

; Wang, Xuefeng

; Li, Maichao

; Fan, Youlin

; He, Yuwei

; Jia, Zhaotong

; Han, Lin

; Liu, Zhen

Advances in Rheumatology

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2023, Volume 63 elocation 39

Resumo: En | Texto: En | PDF: En

Abstract Objectives The deposition of monosodium urate (MSU) crystals within synovial joints and tissues is the initiating factor for gout arthritis. Thus, MSU crystals are a vital tool for studying gout's molecular mechanism in animal and cellular models. This study mainly compared the excellence and worseness of MSU crystals prepared by different processes and the degree of inflammation induced by MSU crystals. Methods MSU crystals were prepared using neutralization, alkali titration, and acid titration methods. The crystals' shape, length, quality, and uniformity were observed by polarized light microscopy and calculated by the software Image J. The foot pad and air pouch models were used to assess the different degrees of inflammation induced by the MSU crystals prepared by the three different methods at different time points. Paw swelling was evaluated by caliper. In air pouch lavage fluid, inflammatory cell recruitment was measured by hemocytometer, and the level of IL-1β TNF- α, and IL-18 by ELISA. Inflammatory cell infiltration was assayed by immunohistochemistry of air pouch synovial slices. Results For the preparation of MSU crystals with the same uric acid, the quantity acquired by the alkalization method was highest, followed by neutralization, with the acid titration method being the lowest. The crystals prepared by neutralization were the longest. The swelling index of the foot pad induced by MSU crystals prepared by acid titration was significantly lower than that of the other methods at 24 h. The inflammatory cell recruitment and level of 1-1β, TNF-α, and IL-18 in air pouch lavage fluid were lowest in animals with crystals prepared by acid titration. IL-1β secretion induced by MSU crystals prepared by acid titration was significantly lower than that of the other two groups, but there was no significant difference in IL-18 secretion between the three groups in THP-1 macrophages and BMDMs. Conclusions All three methods can successfully prepare MSU crystals, but the levels of inflammation induced by the crystals prepared by the three methods were not identical. The degree of inflammation induced by MSU crystals prepared by neutralization and alkalization is greater than by acid titration, but the quantity of MSU crystals obtained by the alkalization method is higher and less time-consuming. Apparently, the window of inflammation triggered by acid titration preparation is shorter compared to other forms of crystal preparation. Overall, MSU crystals prepared by the alkaline method should be recommended for studying the molecular mechanisms of gout in animal and cellular models.

https://doi.org/10.1186/s42358-023-00307-1

The association between dietary fiber and infertility among US women: the National Health and Nutrition Examination Survey, 2013-2018
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Chen, Man-Shuang

; Wang, Dong-Ying

; Gong, Hui-Yu

; Zhang, Hui-Min

; Gao, Jie

; Luo, Song-Ping

Nutrición Hospitalaria

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Dez 2022, Volume 39 Nº 6 Páginas 1333 - 1340

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract Background: studies have shown that dietary factors are linked to female infertility, but the relation between dietary fiber consumption and infertility has not been proven. The purpose of this research was to investigate whether there is an independent association between dietary fiber intake and infertility in American women. Material and methods: a secondary analysis of the National Health and NUTRITION Examination Survey (NHANES) dataset has been conducted, covering three cycles from 2013 to 2018. A total of 3,497 participants were included in the data analysis. The independent and dependent variables of interest were dietary fiber intake and infertility. Covariates included sociodemographic, questionnaire, diet, and physical examination data. Multiple logistic regression and sensitivity analyses were performed to investigate the relationship of dietary fiber intake with infertility. Results: each additional increase in log10 dietary fiber consumption was associated with a 32 % lower risk of infertility (OR, 0.68; 95 % CI, 0.48-0.96). The outcome is still robust in the minimally as well as the fully adjusted model. The possibility of a nonlinear association between dietary fiber intake and infertility was ruled out by the GAM model and smooth curve fitting. The RESULTS showed that there is an inverse linear correlation between dietary fiber intake and infertility. Conclusions: the association between intake of dietary fiber and infertility is linear, and increasing dietary fiber intake may be beneficial for lower infertility.

Resumen Antecedentes: el consumo de fibra dietética es un factor importante en la infertilidad femenina. El objetivo del estudio fue investigar si existe una relación independiente entre el consumo de fibra dietética y la infertilidad en las mujeres estadounidenses. Material y métodos: se realizó un análisis secundario del conjunto de datos de la encuesta nacional de salud y nutrición (NHANES), que abarcó tres ciclos entre 2013 y 2018. Se incluyeron 3497 participantes para el análisis de datos. Las variables independientes y dependientes asociadas fueron la ingesta de fibra dietética y la infertilidad. Las covariables incluyeron datos sociodemográficos, de los cuestionarios, dietéticos y médicos. Se realizó un análisis de regresión logística multivariada y un análisis de sensibilidad para determinar la relación entre el consumo de fibra dietética y la infertilidad. Resultados: cada aumento log10 en el consumo de fibra dietética se asoció con una reducción del 32 % en el riesgo de infertilidad (OR: 0,68; intervalo de confianza del 95 %: 0,48-0,96). En el modelo mínimo y totalmente ajustado, los resultados siguen siendo robustos. El modelo GAM y el ajuste de curvas suavizadas descartaron la posibilidad de una relación no lineal entre la ingesta de fibra dietética y la infertilidad. Los resultados muestran una correlación lineal negativa entre la ingesta de fibra dietética y la infertilidad. Conclusiones: se observó una relación lineal entre la ingesta de fibra dietética y la infertilidad. El aumento de la ingesta de fibra dietética redujo la incidencia de la infertilidad.

https://doi.org/10.20960/nh.04056

RESEARCH ON THE INFLUENCE OF VOLLEYBALL OPTIONAL COURSE ON COLLEGE STUDENTS’ PHYSICAL HEALTH
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Liu, Yanmei

; Zhang, Hui

; Mou, Kerong

Revista Brasileira de Medicina do Esporte

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Out 2022, Volume 28 Nº 5 Páginas 428 - 431

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: Explorar a influência do curso opcional de voleibol sobre a saúde física dos estudantes universitários. Método: Neste estudo, 160 estudantes universitários (n=89, feminino (n=71)) da série 2019 da Escola T foram selecionados como objetos de pesquisa, com idades entre 19-21 anos. Através de revisão de literatura, entrevista, medição e estatísticas matemáticas, este trabalho testa a qualidade da força dos estudantes, a qualidade da velocidade, a qualidade da resistência e a flexibilidade. Resultados: O índice médio de 1000 metros antes e depois do curso eletivo de voleibol para estudantes masculinos, índice médio de 800 metros antes e depois do curso eletivo de voleibol feminino, a comparação do salto em distância, o índice médio de 50 metros entre estudantes masculinos e femininos antes e depois da aula eletiva de voleibol apresentaram uma significante diferença estatística (P < 0,05). Entretanto, o índice médio comparativo dos dados antes e depois da aula eletiva de pull-up, sit-up e flexão sentada após o voleibol não apresenta diferença estatística. Conclusão: O estudo demonstra que o treinamento na aula de vôlei tem um impacto positivo sobre a saúde física dos estudantes universitários. Nível de evidência II; Estudos terapêuticos – investigação de resultados de tratamento.

ABSTRACT Objective: To explore the influence of volleyball elective course on college students’ physical health. Methods: In this study, 160 college students (n=89, female (n=71)) of the 2019 series of School T were selected as research subjects, aged 19-21 years. Through literature review, interview, measurement and mathematical statistics, this paper tests students’ strength quality, speed quality, endurance quality and flexibility. Results: the average index of 1000 meters before and after the elective volleyball course for male students; average index of 800 meters before and after the elective volleyball course for female students; The comparison of long jump and average index of 50 meters between male and female students before and after the elective volleyball class shows a significant statistical difference (P < 0.05). However, the comparative mean index of the data before and after the pull-up, sit-up and sit-up flexion elective class after volleyball shows no statistical difference. Conclusion: The study demonstrates that training in volleyball class has a positive impact on the physical health of college students. Level of evidence II; Therapeutic studies - investigation of treatment results.

RESUMEN Objetivo: Explorar la influencia del curso optativo de voleibol en la salud física de los estudiantes universitarios. Método: En este estudio, se seleccionaron como sujetos de investigación 160 estudiantes universitarios (n=89, mujeres (n=71)) de la serie 2019 de la Escuela T, de entre 19 y 21 años. A través de la revisión de la literatura, la entrevista, la medición y la estadística matemática, este trabajo pone a prueba la calidad de la fuerza, la calidad de la velocidad, la calidad de la resistencia y la flexibilidad de los estudiantes. Resultados: el índice medio de 1000 metros antes y después del curso de voleibol optativo para los alumnos varones; el índice medio de 800 metros antes y después del curso de voleibol optativo para las alumnas; la comparación del salto de longitud y el índice medio de 50 metros entre los alumnos varones y las alumnas antes y después de la clase de voleibol optativo muestra una diferencia estadística significativa (P < 0,05). Sin embargo, el índice medio comparativo de los datos antes y después de la clase electiva de pull-up, sit-up y flexión sentada después del voleibol no muestra ninguna diferencia estadística. Conclusión: El estudio demuestra que el entrenamiento en la clase de voleibol tiene un impacto positivo en la salud física de los estudiantes universitarios. Nivel de evidencia II; Estudios terapéuticos – investigación de resultados de tratamiento.

https://doi.org/10.1590/1517-8692202228052021_0522

SOCCER PLAYER’S PHYSICAL TRAINING FOR PHYSICAL FUNCTION IMPROVEMENT
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Chen, Xi

; Zhang, Hui

Revista Brasileira de Medicina do Esporte

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Out 2022, Volume 28 Nº 5 Páginas 577 - 580

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Introdução: O futebol é um esporte intensamente competitivo. Com o seu desenvolvimento e elevação no nível das técnicas, são apresentadas exigências mais altas para a aptidão física, estratégia e tática dos atletas. Um bom protocolo de treinamento físico é essencial para atingir essas metas. Objetivo: Estudar como os jogadores de futebol podem melhorar sua função física no treinamento físico. Métodos: Os jogadores de futebol de uma escola foram selecionados como objetos de pesquisa. Intervenções de treinamento físico e testes de acompanhamento foram feitos em jogadores de futebol durante o treinamento. O treinamento físico incluiu um teste de função física e um teste de composição corporal. Finalmente, o software SPSS16.0 foi usado para análise estatística dos dados obtidos. Resultados: Os valores médios de concentração de hemoglobina e células vermelhas sanguíneas no teste final dos atletas aumentaram ligeiramente em comparação com o primeiro, a diferença não foi significativa (P>0,05). Entretanto, o índice do hematócritos melhorou significativamente com efeito significativo (P<0,01). Conclusão: O treinamento físico pode reduzir o conteúdo de gordura corporal na função física dos jogadores de futebol e reduzir o peso dos jogadores de futebol. Esse modo de treinamento físico pode ser usado como um padrão de referência para o treinamento físico de outras equipes de futebol de alto nível. Nível de evidência II; Estudos Terapêuticos - Investigação de Resultados.

ABSTRACT Introduction: Soccer is an intensely competitive sport. With its development and elevation in techniques, athletes’ higher demands for physical fitness, strategy, and tactics are presented. An excellent physical training protocol is essential to achieve these goals. Objective: To study how soccer players can improve their physical function in physical training. Methods: Soccer players from a school were selected as research subjects. Physical training interventions and follow-up tests were performed on soccer players during training. Physical training included a physical function test and a body composition test. Finally, SPSS16.0 software was used for statistical analysis of the obtained data. Results: The mean hemoglobin and red blood cell concentration mean values in the athletes’ final test increased slightly compared to the first test; the difference was insignificant (P>0.05). However, the hematocrit index improved significantly (P<0.01). Conclusion: Physical training can reduce the body fat content in the physical function of soccer players and reduce the weight of soccer players. This physical training mode can be used as a reference standard for the physical training of other high-level soccer teams. Evidence Level II; Therapeutic Studies - Investigating the result.

Resumen Introducción: El fútbol es un deporte intensamente competitivo. Con su desarrollo y elevación en el nivel de las técnicas, se presentan mayores exigencias para la aptitud física, la estrategia y la táctica de los atletas. Un buen protocolo de entrenamiento físico es esencial para alcanzar estos objetivos. Objetivo: Estudiar cómo los jugadores de fútbol pueden mejorar su función física en el entrenamiento físico. Métodos: Se seleccionaron jugadores de fútbol de una escuela como sujetos de la investigación. Se realizaron intervenciones de entrenamiento físico y pruebas de seguimiento a los jugadores de fútbol durante el entrenamiento. El entrenamiento físico incluyó una prueba de función física y una prueba de composición corporal. Finalmente, se utilizó el software SPSS16.0 para el análisis estadístico de los datos obtenidos. Resultados: Los valores medios de concentración de hemoglobina y glóbulos rojos en la prueba final de los atletas aumentaron ligeramente en comparación con la primera prueba, la diferencia no fue significativa (P>0,05). Sin embargo, el índice de hematocrito mejoró significativamente con un efecto importante (P<0,01). Conclusión: El entrenamiento físico puede reducir el contenido de grasa corporal en la función física de los futbolistas y reducir el peso de los mismos. Este modo de entrenamiento físico puede utilizarse como norma de referencia para el entrenamiento físico de otros equipos de fútbol de alto nivel. Nivel de evidencia II; Estudios terapéuticos - Investigación de resultados.

https://doi.org/10.1590/1517-8692202228052022_0091

Repair of large traumatic tympanic membrane perforation using ofloxacin otic solution and gelatin sponge
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Li, Xiuguo

; Zhang, Hui

; Zhang, Yuanyuan

Brazilian Journal of Otorhinolaryngology

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Fev 2022, Volume 88 Nº 1 Páginas 9 - 14

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Introdução As grandes perfurações traumáticas da membrana timpânica geralmente apresentam falha de cicatrização e requerem tempos de cicatrização mais longos; poucos estudos compararam os resultados de cicatrização e a audição dessas perfurações obtidos com curativo de Gelfoam® e solução otológica de ofloxacina. Objetivo Comparar os resultados de cicatrização de grandes perfurações traumáticas da membrana timpânica tratadas com Gelfoam®, solução otológica de ofloxacina e cicatrização espontânea. Método Perfurações traumáticas de > 50% de todo o tímpano foram divididas aleatoriamente em três grupos: tratamento com solução otológica de ofloxacina, com curativo de Gelfoam® e grupo de cicatrização espontânea. O resultado da cicatrização e o ganho auditivo foram comparados entre os três grupos após 6 meses. Resultados Foram incluídos nas análises 136 pacientes com grandes perfurações traumáticas de membrana timpânica. As taxas de cicatrização foram de 97,6% (40/41), 87,2% (41/47) e 79,2% (38/48) com a solução otológica de ofloxacina, curativo de Gelfoam® e grupos de cicatrização espontânea, respectivamente (p = 0,041). O tempo médio de cicatrização foi de 13,12 ± 4,61, 16,47 ± 6,24 e 49,51 ± 18,22 dias nesses grupos, respectivamente (p < 0,001). Conclusões O curativo de Gelfoam® e a solução otológica de ofloxacina podem servir como estratégias de tratamento eficazes e de baixo custo para grandes perfurações traumáticas de membrana timpânica. Entretanto, a solução otológica de ofloxacina deve ser autoaplicada diariamente para manter a borda da perfuração úmida, enquanto o curativo de Gelfoam® requer sua remoção e reaplicação periódicas.

Abstract Introduction Traumatic large tympanic membrane perforations usually fail to heal and require longer healing times. Few studies have compared the healing and hearing outcomes between gelatin sponge patching and ofloxacin otic solution. Objectives To compare the healing outcomes of large traumatic tympanic membrane perforations treated with gelatin sponge, ofloxacin otic solution, and spontaneous healing. Methods Traumatic tympanic membrane perforations >50% of the entire eardrum were randomly divided into three groups: ofloxacin otic solution, gelatin sponge patch and spontaneous healing groups. The healing outcome and hearing gain were compared between the three groups at 6 months. Results A total of 136 patients with large traumatic tympanic membrane perforations were included in analyses. The closure rates were 97.6% (40/41), 87.2% (41/47), and 79.2% (38/48) in the ofloxacin otic solution, gelatin sponge patch, and spontaneous healing groups, respectively (p = 0.041). The mean times to closure were 13.12 ± 4.61, 16.47 ± 6.24, and 49.51 ± 18.22 days in these groups, respectively (p < 0.001). Conclusions Gelatin sponge patch and ofloxacin otic solution may serve as effective and inexpensive treatment strategies for traumatic large tympanic membrane perforations. However, ofloxacin otic solution must be self-applied daily to keep the perforation edge moist, while gelatin sponge patching requires periodic removal and re-patching.

https://doi.org/10.1016/j.bjorl.2020.03.007

Shade stress on maize seedlings biomass production and photosynthetic traits
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Yuan, Liuzheng

; Liu, Jiayou

; Cai, Zhiyong

; Wang, Huiqiang

; Fu, Jiafeng

; Zhang, Hongtao

; Zhang, Yundong

; Zhu, Shidie

; Wu, Weihua

; Yan, Haixia

; Zhang, Hui

; Li, Tianqi

; Zhang, Lu

; Yuan, Manman

Ciência Rural

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2022, Volume 52 Nº 3 elocation e20201022

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO: As respostas de duas cultivares de milho (Zea mays L.), ‘LY336’ (tolerante à sombra) e ‘LC803’ (sensível à sombra), ao estresse de sombra em um experimento em vaso conduzido nas safras de 2015 e 2016 foram investigadas. O impacto do tratamento de estresse de sombra de 50% na biomassa da parte aérea, parâmetros fotossintéticos, fluorescência da clorofila e teor de malondialdeído (MDA) foi avaliado. A biomassa da parte aérea dos dois híbridos de milho foi reduzida significativamente pelo tratamento de estresse de sombra, para estresse de sombra 7 d, o LC803 e LY336 foram reduzidos em 56,7% e 44,4% em comparação com a luz natural. Os parâmetros de fluorescência da clorofila de LY336 não foram significativamente afetados pelo estresse de sombra, enquanto aqueles de LC803 foram significativamente afetados, o Fo aumentou sob estresse de sombra, porém Fm, FV / FM e ΦPSII diminuíram sob estresse de sombra. Entre os parâmetros fotossintéticos medidos, a taxa fotossintética líquida (Pn), a condutância estomática (Gs) e a taxa de transpiração diminuíram significativamente em comparação com a luz natural, redução de LY336 e LC803 em 28,0%, 22,2%, 57,7% e 35,5%, 18,9%, 62,4 %, porém a concentração intercelular de CO2 (Ci) aumentou significativamente para as duas cultivares. Sob estresse de sombra para diferentes durações (1, 3, 5, 7 d), os teores de Pn, Gs, Ci e MDA diferiram significativamente entre as duas cultivares. Os resultados indicam que diferentes genótipos de milho apresentam diferentes respostas ao sombreamento. Os genótipos tolerantes à sombra são apenas fracamente afetados pelo estresse de sombra.

ABSTRACT: The responses of two maize (Zea mays L.) cultivars, ‘LY336’ (shade tolerant) and ‘LC803’ (shade sensitive), to shade stress in a pot experiment conducted in the 2015 and 2016 growing seasons were investigated. The impact of 50% shade stress treatment on shoot biomass, photosynthetic parameters, chlorophyll fluorescence, and malondialdehyde (MDA) content was evaluated. The shoot biomass of the two maize hybrids was decreased significantly by shade stress treatment, for shade stress 7 d, the LC803 and LY336 were reduced by 56.7% and 44.4% compared with natural light. Chlorophyll fluorescence parameters of LY336 were not significantly affected by shade stress, whereas those of LC803 were significantly affected, the Fo increased under shade stress; however Fm, FV/FM and ΦPSII were decreased under shade stress. Among photosynthetic parameters measured, net photosynthetic rate (Pn), stomatal conductance (Gs), and transpiration rate were significantly decreased compared with natural light, LY336 and LC803 reduction by 28.0%, 22.2%, 57.7% and 35.5%, 18.9%, 62.4%; however, intercellular CO2 concentration (Ci) was significantly increased, for the two cultivars. Under shade stress for different durations (1, 3, 5, 7 d), Pn, Gs, Ci, and MDA content differed significantly between the two cultivars. Results indicated that different maize genotypes showed different responses to shading. Shade-tolerant genotypes are only weakly affected by shade stress.

https://doi.org/10.1590/0103-8478cr20201022 118 downloads

10.

Effect of altitude on reproductive ingredient and sex allocation of different colors of Anemone obtusiloba in populations
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DING, GongTao

; LI, Bing

; LIU, ZuoJun

; MA, WenJin

; JIA, HongZhen

; LIU, XiaoBo

; ZHANG, Hui

; ZHAO, ZhiGang

; ZHANG, XiaoXue

; ZHANG, XiaoYan

Food Science and Technology

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2022, Volume 42 elocation e34421

Resumo: En | Texto: En | PDF: En

Abstract In this study, we aimed to explore the effect of altitude on reproductive ingredient and sex allocation of different colors of Anemone obtusiloba in populations. The variations of reproductive ingredient and sex allocation of three colors of Anemone obtusiloba in different four altitudinal gradients at the eastern Qinghai Tibetan Plateau were examined. Our results showed that with the increased altitude, gynoecium/flower, androceium/flower and gynoecium/individual were increased, but androceium/individual, gynoecium number/flower, androceium number/flower, gynoecium number/ individual and androceium number/individual in three flower color of Anemone obtusiloba were decreased. Besides, male allocation and ♂/♀ were also decreased, which showed female-biased sex allocation. Furthermore, in the four altitudinal gradients, the individual size of same color was positively correlated with reproductive ingredient, and altitude had a direct impact on size-dependent reproductive ingredient. However, there were not certain correlations between male allocation, ♂/♀ and individual size in the same color of Anemone obtusiloba. Moreover, in the four altitudinal gradients, the reproductive investment of same color was positively correlated with gynoecium and androceium, but there were not certain correlations between male allocation, ♂/♀ and reproductive investment. In conclusion, altitude had a significant effect on reproductive ingredient and sex allocation in different colors of Anemone obtusiloba. Different colors of Anemone obtusiloba all increased of female function with the increased altitude. However, there were difference in influence mechanism of altitude on size-dependent reproductive ingredient and distribution between female and male function of resource.

https://doi.org/10.1590/fst.34421

11.

Separation of γ-oryzanol from immature rice seeds by nanofiltration membrane
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LI, Dan

; ZHANG, Chao

; ZHANG, Hui-min

; ZHANG, Dong-jie

; ZUO, Feng

Food Science and Technology

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2022, Volume 42 elocation e12922

Resumo: En | Texto: En | PDF: En

Abstract γ-Oryzanol, which is rich in rice seeds, is natural phytonutrition with many functions such as antioxidant. However, γ-oryzanol has a large loss in the traditional processing, resulting in a huge waste of available resources. In this study, the rice seeds highest content of γ-oryzanol during the development of rice seeds was selected and separated processes by nanofiltration. Several nanofiltration membranes were dramatically applied to condensing phytonutrition under 0.5 Mpa pressure and the flux ranged from 5.8 to 7.7 kg•m-2•h-1. The first processing supplied the separation improving ethanol-extraction system enrichment in γ-oryzanol. In the second, refining ethanol-extraction dramatically reduced the content of free fatty acids, while γ-oryzanol in the retention solution was further significantly increased. Moreover, the isolated γ-oryzanol added in the soybean oil, notably improved antioxidant ability of oil. Our founding can be widely used in the functional food manufacturing and also provides as an available method.

https://doi.org/10.1590/fst.12922

12.

Saúde Cardiovascular e Fibrilação ou Flutter Atrial: Um Estudo Transversal do ELSA-Brasil
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Santos, Itamar S.

; Lotufo, Paulo A.

; Goulart, Alessandra C.

; Brant, Luisa C. C.

; Pinto Filho, Marcelo M

; Pereira, Alexandre C.

; Barreto, Sandhi M.

; Ribeiro, Antonio L. P.

; Thomas, G Neil

; Lip, Gregory Y. H.

; Bensenor, Isabela M.

; Arasalingam, Ajini

; Beane, Abi

; Bensenor, Isabela M

; Brocklehurst, Peter

; Cheng, Kar Keung

; El-Bouri, Wahbi

; Feng, Mei

; Goulart, Alessandra C

; Greenfield, Sheila

; Guo, Yutao

; Guruparan, Mahesan

; Gusso, Gustavo

; Gooden, Tiffany E

; Haniffa, Rashan

; Humphreys, Lindsey

; Jolly, Kate

; Jowett, Sue

; Kumarendran, Balachandran

; Lancashire, Emma

; Lane, Deirdre A

; Li, Xuewen

; Lip (Co-PI), Gregory Y.H.

; Li, Yan-guang

; Lobban, Trudie

; Lotufo, Paulo A

; Manseki-Holland, Semira

; Moore, David J

; Nirantharakumar, Krishnarajah

; Olmos, Rodrigo D

; Paschoal, Elisabete

; Pirasanth, Paskaran

; Powsiga, Uruthirakumar

; Romagnolli, Carla

; Santos, Itamar S

; Shantsila, Alena

; Sheron, Vethanayagam Antony

; Shribavan, Kanesamoorthy

; Szmigin, Isabelle

; Subaschandren, Kumaran

; Surenthirakumaran, Rajendra

; Tai, Meihui

; Neil Thomas (Co-PI), G

; Varella, Ana C

; Wang, Hao

; Wang, Jingya

; Zhang, Hui

; Zhong, Jiaoyue

Arquivos Brasileiros de Cardiologia

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2022, Nº ahead

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Fundamento A associação entre o status de saúde cardiovascular ideal ( ideal cardiovascular health ( ICVH) e diagnóstico de fibrilação ou flutter atrial (FFA) foi menos estudado em comparação a outras doenças cardiovasculares. Objetivos Analisar a associação entre o diagnóstico de FFA e métricas e escores de ICVH no Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil). Métodos Este estudo analisou dados de 13141 participantes com dados completos. Os traçados eletrocardiográficos foram codificados de acordo com o Sistema de Minnesota, em um centro de leitura centralizado. As métricas do ICVH (dieta, atividade física, índice de massa corporal, tabagismo, glicemia de jeju, e colesterol total) e escores do ICVH foram calculados conforme proposto pela American Heart Association . Modelos de regressão logística bruta e ajustada foram construídos para analisar associações de métricas e escores do ICVH com diagnóstico de FFA. O nível de significância foi estabelecido em 0,05. Resultados A idade mediana da amostra foi de 55 anos, e 54,4% eram mulheres. Nos modelos ajustados, os escores de ICVH não apresentaram associação significativa com diagnóstico de FFA prevalente [odds ratio (OR):0,96; intervalo de confiança de 95% (IC95%):0,80-1,16; p=0,70). Perfis de pressão arterial ideal (OR:0,33; IC95%:0,1-0,74; p=0,007) e colesterol total ideal (OR:1,88; IC95%:1,19-2,98; p=0,007) foram significativamente associados com o diagnóstico de FFA. Conclusões Não foram identificadas associações significativas entre escores de ICVH global e diagnóstico de FFA após ajuste multivariado em nossas análises, devido, ao menos em parte, às associações antagônicas da FFA com métricas de pressão arterial e de colesterol total do ICVH. Nossos resultados sugerem que estimar a prevenção da FFA por meio de escore de ICVH global pode não ser adequado, e as métricas do ICVH devem ser consideradas separadamente.

Abstract Background The association between ideal cardiovascular health (ICVH) status and atrial fibrillation or flutter (AFF) diagnosis has been less studied compared to other cardiovascular diseases. Objective To analyze the association between AFF diagnosis and ICVH metrics and scores in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Methods This study analyzed data from 13,141 participants with complete data. Electrocardiographic tracings were coded according to the Minnesota Coding System, in a centralized reading center. ICVH metrics (diet, physical activity, body mass index, smoking, blood pressure, fasting plasma glucose, and total cholesterol) and scores were calculated as proposed by the American Heart Association. Crude and adjusted binary logistic regression models were built to analyze the association of ICVH metrics and scores with AFF diagnosis. Significance level was set at 0.05. Results The sample had a median age of 55 years and 54.4% were women. In adjusted models, ICVH scores were not significantly associated with prevalent AFF diagnosis (odds ratio [OR]:0.96; 95% confidence interval [95% CI]:0.80-1.16; p=0.70). Ideal blood pressure (OR:0.33; 95% CI:0.15–0.74; p=0.007) and total cholesterol (OR:1.88; 95% CI:1.19–2.98; p=0.007) profiles were significantly associated with AFF diagnosis. Conclusions No significant associations were identified between global ICVH scores and AFF diagnosis after multivariable adjustment in our analyses, at least partially due to the antagonistic associations of AFF with blood pressure and total cholesterol ICVH metrics. Our results suggest that estimating the prevention of AFF burden using global ICVH scores may not be adequate, and ICVH metrics should be considered in separate.

https://doi.org/10.36660/abc.20210970

13.

Gynura segetum induces hepatic sinusoidal obstruction syndrome in mice by impairing autophagy
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Zhang, Hui

; Jia, Shu

; Jin, Lianyu

; MB, Jianzuo Yao

; Shen, Zhihong

; Wu, Jingyi

; Yao, Xiaokun

; Chen, Danwei

; Zhang, Congcong

; Yu, Shufang

; Zhu, Ningwei

; Jin, Lexiao

; Yao, Xiaomin

Acta Cirúrgica Brasileira

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2021, Volume 36 Nº 11 elocation e361104

Resumo: En | Texto: En | PDF: En

ABSTRACT Purpose: To investigate the underlying mechanism of hepatic sinusoidal obstruction syndrome (HSOS) induced by Gynura segetum by measuring autophagy in mouse models. Methods: The model group was administered G. segetum (30 g/kg/d) by gavage, while the normal control group was administered an equal volume of saline daily for five weeks. Serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), hepatic histopathological examinations, and Masson staining were performed to evaluate liver injury. Liver intercellular adhesion molecule-1 (ICAM-1) and P-selectin were evaluated by immunohistochemistry. Hepatocellular apoptosis was assessed using the terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) assay. Protein expression levels of autophagy markers were measured using Western blot analysis. Results: Gynura segetum was found to significantly induce liver injury compared with control mice, as evidenced by the increase of serum transaminases, a decrease in triglyceride levels, and histopathological changes in mice. Gynura segetum remarkably induced hepatocellular apoptosis and upregulated the expressions of ICAM-1 and P-selectin and also downregulated the protein expression levels of LC3, Atg12 and cytoplasmic polyadenylation element binding protein. Conclusions: Our results suggested that G. segetum induced liver injury with HSOS, and it was partly due to its ability to impair the autophagy pathway.

https://doi.org/10.1590/acb361104

14.

Differential response of denitrifying community to the application of green manure and reduced chemical fertilizer in a paddy soil
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Fang, Yu

; Wang, Fei

; Jia, Xianbo

; Zhang, Hui

; Lin, Chenqiang

; Chen, Longjun

; Chen, Jichen

Chilean journal of agricultural research

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Set 2020, Volume 80 Nº 3 Páginas 393 - 404

Resumo: En | Texto: En | PDF: En

ABSTRACT Denitrification could lead to N loss from agricultural soil resulting in a low rate of N availability by crops. We investigated the response of nirK and nirS denitrifiers in a paddy soil to the incorporation of green manure and reduced chemical fertilizer. Soil samples were collected from plots of a short-term fertilization experiment initiated in 2009. The treatments were no chemical fertilizer, no Chinese milk vetch (Astragalus sinicus L., CK), chemical fertilizer (NPK), Chinese milk vetch (MV) plus 80% chemical fertilizer (MF80), MV plus 60% chemical fertilizer (MF60) and MV plus 40% chemical fertilizer (MF40). Abundance and community composition of nirK and nirS denitrifiers were analyzed using quantitative PCR and Miseq sequencing. Reduced chemical fertilizer did not reduce content of total N and available N in soils amended with green manure. Abundances of nirK and nirS genes in different treatments were 1.04 ×108 to 4.89×108 and 1.22 ×107 to 7.04 ×107 copies g-1 soil, respectively, which were significantly higher in NPK treatment than those in soils with green manure. NirK abundance was positively correlated with the potential denitrifying activity (PDA) (r2 = 0.827, p < 0.01). Green manure combination with reduced chemical fertilizer significantly changed the community structure of nirK denitrifiers but not nirS denitrifiers relative to soils amended with chemical fertilizer and unfertilized soil. Shifts of community structure of nirK denitrifiers were closely associated with soil organic matter (r2 = 0.623, p = 0.003), available N (r2 = 0.507, p = 0.01), pH (r2 = 0.661, p = 0.006), and PDA (r2 = 0.633, p = 0.005). In conclusion, nirK-type denitrifying community was more sensitive to the incorporation of green manure and reduced chemical fertilizer and they played a more important role in the denitrification process in this study.

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15.

Total Panax notoginseng saponin inhibits balloon injury-induced neointimal hyperplasia in rat carotid artery models by suppressing pERK/p38 MAPK pathways
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Yang, Zheng

; Zhang, Hui

; An, Ming

; Bian, Mengni

; Song, Miao

; Guo, Xiaohua

; Liu, Quanli

; Qiu, Min

Brazilian Journal of Medical and Biological Research

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Jan 2020, Volume 53 Nº 1 elocation e9085

Resumo: En | Texto: En | PDF: En

Total Panax notoginseng saponin (TPNS) is the main bioactivity compound derived from the roots and rhizomes of Panax notoginseng (Burk.) F.H. Chen. The aim of this study was to investigate the effectiveness of TPNS in treating vascular neointimal hyperplasia in rats and its mechanisms. Male Sprague-Dawley rats were randomly divided into five groups, sham (control), injury, and low, medium, and high dose TPNS (5, 10, and 20 mg/kg). An in vivo 2F Fogarty balloon-induced carotid artery injury model was established in rats. TPNS significantly and dose-dependently reduced balloon injury-induced neointimal area (NIA) (P<0.001, for all doses) and NIA/media area (MA) (P<0.030, for all doses) in the carotid artery of rats, and PCNA expression (P<0.001, all). The mRNA expression of smooth muscle (SM) α-actin was significantly increased in all TPNS groups (P<0.005, for all doses) and the protein expression was significantly increased in the medium (P=0.006) and high dose TPNS (P=0.002) groups compared to the injury group. All the TPNS doses significantly decreased the mRNA expression of c-fos (P<0.001). The medium and high dose TPNS groups significantly suppressed the upregulation of pERK1/2 protein in the NIA (P<0.025) and MA (P<0.004). TPNS dose-dependently inhibited balloon injury-induced activation of pERK/p38MAPK signaling in the carotid artery. TPNS could be a promising agent in inhibiting cell proliferation following vascular injuries.

https://doi.org/10.1590/1414-431x20199085 1076 downloads

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